OUR RESEARCH FOCUS
Our research focuses on studying the molecular signaling systems and transcriptional networks that orchestrate organogenesis during embryonic development. To this aim we use mostly the mouse with its superbe genetics as a model embryo. The developing embryo is a stunning testimony to the intricate mechanisms that control patterning and differentiation of functional tissues and organs and to the evolutionary variations in these mechanisms that gave rise to the diversity of modern vertebrates. One of our main focuses is to study the self-regulatory signaling systems and gene regulatory networks that control vertebrate limb development.
NEWS & JOBS
Read the blog entry on the University of Basel website now:
"Robust gene networks from the depths of our evolutionary history"
Read the article on Swiss National Radio of PD Dr. Aimée Zuniga and Prof. Dr. Rolf Zeller about research with mouse embryos
Our research featured on Swiss National Radio on the occasion of CRISPR/Cas 9 Nobel prize award to E. Charpentier and J. Doudna.
PD Dr. Aimée Zuniga has been elected a Fellow of the Royal Society of Biology (FRSB)
Gamart J., et al. 2021
SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning
Jhanwar S., et al. 2021
Conserved and species-specific chromatin remodeling and regulatory dynamics during mouse and chicken limb bud development
Malkmus J., et al. 2021
Spatial regulation by multiple Gremlin1 enhancers provides digit development with cis-regulatory robustness and evolutionary plasticity
OUR GENEROUS SUPPORTERS
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University of Basel
Departement of Biomedicine